The following residences are associated with the Pontifical University of the Holy Cross:

The Sedes Sapientiae Ecclesiastical International College is located in the Trastevere District. It is a seminary erected by the Holy See and designed to offer formation within Rome to candidates for the priesthood who come from Dioceses and ecclesiastical districts around the world.

The Tiberino College for Priests is located at the foot of the Gianicolo in the ancient Casino de' Rossi. It was built between the end of the fifteenth and beginning of the sixteenth centuries. Its main office is located on Via di San Francesco di Sales no. 27.

The Altomonte College for Priests is found on Via di Torrerossa no. 94/B. Close to St. Peter's and well connected to the city center.