The specific mission of the Pontifical University of the Holy Cross is to enrich one’s understanding of the faith while increasing one’s capacity to dialogue with contemporary culture.

The spirit, vision and commitment that gave rise to universities in Europe centuries ago is the same that inspires the intellectual rigor of research at the service of a faith at Santa Croce. The University seeks an understanding of the faith that impacts a person’s life, better able to give an account of the hope that is in him.

The Santa Croce tries to confront the challenges of today's world by viewing areas of concern as opportunities, forming men and women—priests, religious, lay persons—whose profound and intellectually sound faith is able to enter into dialogue with modernity, advocating Christ convincingly and with conviction.